CDH15 (C-term) Peptide
产品名称： CDH15 (C-term) Peptide
英文名称： CDH15 (C-term) Peptide
产品编号： P0406
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CDH15.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CDH15.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation.
Kang JS, Feinleib JL, Knox S, Ketteringham MA, Krauss RS.Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3989-94. Epub 2003 Mar 12.
- 2.
- The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration.
Hollnagel A, Grund C, Franke WW, Arnold HH.Mol Cell Biol. 2002 Jul;22(13):4760-70.
- 3.
- Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release.
Meigs TE, Fields TA, McKee DD, Casey PJ.Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):519-24. Epub 2001 Jan 2.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of CDH15 (arrow) using rabbit CDH15 polyclonal antibody (Cat # PAB3082). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDH15 gene (Lane 2) (Origene Technologies).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with CDH15 polyclonal antibody (Cat # PAB3082) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 1013
- Protein Accession#:
- NP_004924;P55291
- Gene Name:
- CDH15
- Gene Alias:
- CDH14,CDH3,CDHM,MCAD
- Gene Description:
- cadherin 15, type 1, M-cadherin (myotubule)
- Omim ID:
- 114019
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq
- Other Designations:
- M-cadherin,cadherin 15,cadherin 15, M-cadherin (myotubule),cadherin-14,cadherin-3,muscle-cadherin,myotubule-cadherin
- Gene Pathway