HAP1 polyclonal antibody
产品名称： HAP1 polyclonal antibody
英文名称： HAP1 polyclonal antibody
产品编号： PAB4703
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HAP1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human HAP1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya KNat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21.
- 2.
- A human HAP1 homologue. Cloning, expression, and interaction with huntingtin.
Li SH, Hosseini SH, Gutekunst CA, Hersch SM, Ferrante RJ, Li XJ.J Biol Chem. 1998 Jul 24;273(30):19220-7.
- 3.
- A huntingtin-associated protein enriched in brain with implications for pathology.
Li XJ, Li SH, Sharp AH, Nucifora FC Jr, Schilling G, Lanahan A, Worley P, Snyder SH, Ross CA.Nature. 1995 Nov 23;378(6555):398-402.
- Entrez GeneID:
- 9001
- Protein Accession#:
- HAP1_HUMAN
- Gene Name:
- HAP1
- Gene Alias:
- HAP2,HIP5,HLP,hHLP1
- Gene Description:
- huntingtin-associated protein 1
- Omim ID:
- 600947
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000164747,huntingtin-associated protein 2,neuroan 1
- Gene Pathway