PDCD1 polyclonal antibody
产品名称： PDCD1 polyclonal antibody
英文名称： PDCD1 polyclonal antibody
产品编号： PAB6790
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of PDCD1.
- Immunogen:
- A synthetic peptide corresponding to human PDCD1.
- Sequence:
- C-GELDFQWREKTPE
- Host:
- Goat
- Theoretical MW (kDa):
- 31.7
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A putative regulatory polymorphism in PD-1 is associated with nephropathy in a population-based cohort of systemic lupus erythematosus patients.
Nielsen C, Laustrup H, Voss A, Junker P, Husby S, Lillevang ST.Lupus. 2004;13(7):510-6.
- Entrez GeneID:
- 5133
- Protein Accession#:
- NP_005009.1
- Gene Name:
- PDCD1
- Gene Alias:
- CD279,PD1,SLEB2,hPD-1,hPD-l
- Gene Description:
- programmed cell death 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
- Other Designations:
- -
- Related Disease
- Addison Disease
- Alveolitis, Extrinsic Allergic
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Carcinoma, Squamous Cell
- Choriocarcinoma
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 1
- Disease Progression
- Disease Susceptibility
- Genetic Predisposition to Disease
- Graves Disease
- Hydatidiform Mole
- Inflammation
- Kidney Diseases
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive